منابع مشابه
Red blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management.
Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious complications for the patient including life-threatening delayed hemolytic transfusion reactions and difficulty in finding compatible units, which can cause transfusion delays. In this review, we discuss the risk fac...
متن کاملPrevention of Rh alloimmunization.
OBJECTIVE To provide guidelines on use of anti-D prophylaxis to optimize prevention of rhesus (Rh) alloimmunization in Canadian women. OUTCOMES Decreased incidence of Rh alloimmunization and minimized practice variation with regards to immunoprophylaxis strategies. EVIDENCE The Cochrane Library and MEDLINE were searched for English-language articles from 1968 to 2001, relating to the preven...
متن کاملPlatelet immunology and alloimmunization
Platelets express a variety of immunogenic markers on the cell surface. Some of these antigens are shared with other cell types as in the case of HLA antigens, which are shared with virtually all nucleated cells in the body, whereas others are observed to be essentially platelet specific. This chapter reviews the antigens expressed on platelets, the various patterns of alloimmunization to these...
متن کاملO6: Pathophysiology of Anxiety Disorders
The most important risk factors for anxiety disorders include genes, early life stress, and current stress. These factors do not act independently but interact with each other throughout human development through examples such as epigenetic modifications and complex forms of learning. The neural substrate of pathological anxiety includes hyperactivity in the amygdala and other limbic brain regi...
متن کاملWorking together to block alloimmunization.
The discovery of ABO(H) blood group antigens resulted in the birth of transfusion medicine and allowed for the first time the use of a laboratory test that could predict immunologic outcomes prior to transfusion. Although ABO(H) antibody testing continues to represent one of the first and most common examples of personalized medicine, it was not until many years later that the existence of non-...
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ژورنال
عنوان ژورنال: Transfusion Medicine and Hemotherapy
سال: 2019
ISSN: 1660-3796,1660-3818
DOI: 10.1159/000501861